I prefer the path of traditional publishing but there are many who don't. And, if you have an entrepreneurial spirit, a thick skin, and lots of energy, this may indeed be the path for you.
Joe Konrath has been all over the media lately, explaining how he's been able to make good money through self-publishing. (He's also been traditionally published.) I haven't read his books, but his advice seems sound.
New! "The Self-epublishing Bubble," by Ewan Morrison
Fascinating look at self e-publishing according to economist Hyman Minsky's Financial Instability Hypothesis. This resonates for me: "...the vast majority of the newly self-epublished authors discover that they have sold less than 100 books each. They then discover that this was in fact the business model of Amazon and other epub platforms in the first place..."
New! "The Big Reasons Indie Authors Aren't Taken Seriously," by Melissa Foster and Amy Edelman
Excellent points that should be considered by anyone who wants to pursue self-publishing. I especially agree with #1: bad editing.
Blake Crouch becomes yet another success story. But here's a telling quote: "Amazon’s Kindle store is overloaded right now with a bunch of folks who think they can publish their high school diary and make a lot of money," said Crouch.
Self-publishing phenom Amanda Hocking tells all. Frankly, I don't think this is very well written (which makes me leery of her books), but it definitely provides some insight into her success. I could discuss this all day, so I'll stop here.
A thoughtful and detailed article that will help writers decide whether to self-publish; and, if they decide to do so, it will save them a lot of work. Carnoy's book was later picked up by a traditional publisher, prompting him to observe that, "Self-publishing should be treated as the minor leagues of the book world."
New! "Roll Your Own E-Books," Wired
This wiki has a ton of information for the DIY enthusiast.